GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs11190604 | 1 | rs4919470 | chr10:102298920 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919471 | chr10:102299239 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs4919472 | chr10:102315864 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs2028299 | 1 | rs4932148 | chr15:90394356 | AP3S2 | chr15:90373832-90456222:- | -0.75 | -6.51 | 2.35E-8 | Type 2 diabetes |
| UVM | cis | rs10935120 | 1 | rs4955485 | chr3:134295843 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs10935120 | 1 | rs4955555 | chr3:134286427 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs10935120 | 1 | rs4974483 | chr3:134219001 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs4974484 | chr3:134219019 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 6.95 | 4.49E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs4974493 | chr3:134219993 | ANAPC13 | chr3:134196547-134204865:- | 0.46 | 7.06 | 3.0E-9 | Height |
| UVM | cis | rs4974559 | 1 | rs4974559 | chr4:1380848 | CRIPAK | chr4:1385340-1389782:+ | -0.75 | -4.67 | 1.96E-5 | Systolic blood pressure |
| UVM | cis | rs568617 | 1 | rs507062 | chr11:65661656 | SNX32 | chr11:65601410-65621170:+ | 0.62 | 5.14 | 3.8E-6 | Crohn's disease |
| UVM | cis | rs78153629 | 1 | rs55788133 | chr15:40664239 | C15orf23 | chr15:40674922-40686488:+ | 0.92 | 6.6 | 1.72E-8 | Heschl's gyrus morphology |
| UVM | cis | rs10935120 | 1 | rs55913793 | chr3:134285968 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs9902453 | 1 | rs55971458 | chr17:28427016 | EFCAB5 | chr17:28256874-28435469:+ | 0.4 | 4.97 | 6.82E-6 | Coffee consumption (cups per day) |
| UVM | cis | rs2985684 | 1 | rs56098064 | chr14:50105849 | RPL36AL | chr14:50085407-50087349:- | 0.54 | 5.79 | 3.51E-7 | Carotid intima media thickness |